Roche and Atea Pharmaceutical are collaborating to develop, manufacture, and distribute Atea’s investigational oral direct-acting antiviral AT-527, which acts by blocking the viral RNA polymerase enzyme needed for viral replication. It is currently undergoing phase 2 clinical trial for hospitalized patients with moderate COVID-19, with phase 3 clinical trial expected …
Read More »Takeda to bring 50M Moderna coronavirus shots to Japan
Japanese drug maker Takeda has entered into collaboration with Massachusetts biotech Moderna to bring 50 million doses of its mRNA-based COVID-19 shots to Japanese shores. Takeda will import and distribute mRNA-1273 starting in the first half of 2021, besides handling local regulatory approvals. Moderna’s vaccine is currently undergoing a 30,000-patient …
Read More »Utility of Various Biomarkers in Management of COVID-19
The COVID-19 pandemic has sparked off mounting crisis in every sphere of our lives, and we are realizing that this unceasing outbreak is yet to beget profound consequences. WHO announced COVID-19 as a pandemic on March 11, 2020.1 The early strategy to mitigate this pandemic has been largely limited to …
Read More »Me and My Lockdown Me-Time
They say the hardest person to live with is yourself. I totally agree. I compared myself to a popcorn, bubbling with so much energy and zest for life. C’mon, look around, there’s so much to do, so much to learn, so many people to meet. I felt like 24 hours …
Read More »Pandemic & Mental Health
One of the biggest challenges we all are facing right now is how to manage enormous disruption to our normal lives. Our work, home, and social life have been turned upside down, and we are finding new ways to continue to do what we had been doing. We are getting …
Read More »Impact of COVID-19 on Mental Health and the Stigma of Mental Illness
It started out with the news about the new virus that emerged in China that had claimed many lives. However, here in Nepal, we didn’t take it seriously. Of course not! Why would we? It’s not something that was happening in our country, right? As the news of rising cases …
Read More »WHO & the USA
COVID-19 is an unprecedented humanitarian crisis that has wreaked havoc on countries, economies, and communities globally. The pandemic has resulted in governments, international and national non-government organizations, and intergovernmental organizations joining hands in solidarity to fight the spread of the SARS-CoV-2. The World Health Organization (WHO) has been at the …
Read More »COVID-19 Convalescent Plasma: To Use or Not To Use
What is it? The dictionary meaning of the word convalescence is recovery. A patient who recovers from a given disease and develops high titres of antibodies can become a donor of such antibodies after his/her recovery. The extra vascular component of these antibodies is difficult to collect, but the intravascular …
Read More »COMMON QUERIES ABOUT VACCINES
How do vaccines work? Vaccines, which are made from killed, weakened, or partial version of specific pathogens, prime the body’s immune system against future attacks by those pathogens. So, following vaccination, in case of an attack by a particular pathogen, the immune system will recognize it and fight it off. …
Read More »Influenza and COVID-19
As far as similarities between influenza and COVID-19 are concerned, both have similar presentation, in that they both cause respiratory disease presenting as a wide range of illness, from asymptomatic or mild to severe disease and death. Because both are transmitted by contact, droplets, and fomites, they require the same …
Read More »