Amar B. Shrestha

Recent Trends in Testosterone Replacement Therapy

Although TRT has been gaining popularity over the years and is often prescribed for increasing libido and improving erectile function, the US FDA has only approved it for clinical hypogonadism, which is defined by The American Association of Clinical Endocrinologists as a decrease in sperm or testosterone production (testicular function). …

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Acupuncture Gaining New Importance

Due to the alarming opioid crisis in America, doctors are increasingly looking towards non-pharmacologic ways to treat pain. Among the many methods available, such as massage therapy, spine manipulative therapy, music therapy, etc., acupuncture is considered to be at the forefront in managing chronic pain, especially lower back pain, knee …

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Managing the Pain

Injury, surgery, and certain medical conditions like arthritis, back problems, and cancer are the most common causes of pain in adults, and headache and back pain, along with pain in the neck, limbs, and shoulders, are the ones that are most commonly reported. Pain is a complex protective mechanism that …

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Top Pharma Drugs in 2025

According to a forecast by analysts of GlobalData, a British data analytics and consulting firm, Merck’s Keytruda is expected to reach the top of the bestselling pharma list in 2025, with sales of $22.5 billion. Keytruda (pembrolizumab), a humanized antibody used in cancer immunotherapy, is used for the treatment of …

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Huge Milestone In Skin Cancer Treatment

Ten years ago, many patients with advanced melanoma died within six-nine months of diagnosis, with only about one in twenty surviving the disease. If caught early on, patients have a good chance of survival, but with time, the cancer becomes more aggressive and metastatic, and mortality rates fall sharply. Now, …

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Breast Cancer Sleeper Cells

medicosnext

Seventy percent of all breast cancers are estrogen-receptor positive, and hormone therapies are used to treat this type of breast cancer. A course of hormone therapy (either tamoxifen or aromatase inhibitors) targeting estrogen receptors are given after first removing the tumor with surgery. But, about 30 percent of patients taking …

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All Work and No Play…

All Work and No Play...

A new World Health Organization (WHO) study published in The Lancet Child & Adolescent Health Journal has found that more than 80% of school kids worldwide (85% of girls and 78% of boys, aged 11 to 17 years) did not meet the current recommendation of at least one hour of …

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Promising Treatment for Pancreatic Cancer

  Pancreatic cancer (PC), an aggressive malignancy with one of the highest mortality rates amongst cancers, is characterized by rapid development, fast growth, and frequent lymph node metastasis, which contribute to its very poor prognosis. The overall five-year survival rate of patients with pancreatic cancer is only about nine percent …

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Opioid Epidemic in the U.S.A.

An opioid epidemic has been declared in the United States, with opioid-related drug overdose deaths reaching 47,600 in 2017. In 1999, such deaths numbered 8,048. According to a CNBC report under the heading, “Americans consume vast majority of the world’s opioids” (April 27, 2016, https://cutt.ly/QF5da2), 80% of the roughly 300 …

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The Scourge of Drug Addiction

Addiction is a medical disorder that affects the brain and causes changes in an individual’s behavior, and it is a problem that affects a large number of people around the globe, with youth being particularly susceptible to the scourge. Broadly speaking, illicit drugs, tobacco, and alcohol are substances that may …

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