Medicosnext
Coauthor Zhibo Liu of a research on risk factors for death from COVID-19 identified in Wuhan patients, has stated that, “Older age, showing signs of sepsis on admission, underlying diseases like high blood pressure and diabetes, and the prolonged use of noninvasive ventilation were important factors in the deaths of these patients.” Abnormal blood clotting was also a factor. The first such study to examine risk factors associated with death among adults hospitalized with COVID-19, it was led by Fei Zhou, MD, from the Chinese Academy of Medical Sciences, who along with his colleagues conducted a retrospective, multicenter cohort study of 191 patients, out of which 137 were discharged, while 54 died in the hospital.
Comparison of various data from electronic medical records between survivors and those who died revealed that, 91 (48%) had comorbidity, the most common being hypertension (30%), followed by diabetes (19%) and coronary heart disease (8%). The chance of death increased with age (the average age of survivors was 52 years compared to 69 for those who died), higher Sequential Organ Failure Assessment (SOFA) score (which assesses rate of organ failure in intensive care units), and D-dimer level exceeding 1 mcg/L on admission (which indicates increased risk of abnormal blood clotting). Non-survivors also had higher frequencies of respiratory failure, sepsis, and secondary infections, compared to survivors.
Ref: MDedge News , March 11, 2020, https://urlzs.com/Dj9zk
